This is right now’s version of The Download, our weekday publication that gives a day by day dose of what’s occurring on this planet of expertise.
Montana’s plan to change into an experimental medical hub simply pushed ahead
As of this week in Montana, biotech firms whose medication have been via preliminary testing—generally in as few as 10 wholesome folks—will pay $12,500 to use to a newly established assessment board for approval.
Once its remedy is rubber-stamped, the corporate can promote it through experimental remedy clinics, the primary of which is prone to be up and operating across the finish of this yr.
Montana’s newest right-to-try laws is exclusive. Access to medication is theoretically out there to anybody who provides knowledgeable consent and will pay. For some, particularly folks within the longevity group, that’s a hopeful and thrilling prospect. But to others, it’s unethical and harmful.
Read our story to find out about the place this will likely all be headed.
—Jessica Hamzelou
Montana’s new “proper to attempt” regulation can’t come quickly sufficient for some
Kris DeVault is determined.
His son, Brody, born in March 2023, has one thing referred to as creatine transporter deficiency—a uncommon situation during which the mind and muscle tissues lack the power they should develop.
There aren’t any cures for Brody’s situation. But DeVault has realized of an organization growing a drug that may assist. That drug remains to be within the early levels of growth and has solely been examined in animals and a small variety of wholesome adults. Doctors can’t prescribe it.
DeVault is aware of the drug won’t work. But he’s doing all he can to entry it regardless. Read our story about DeVault’s efforts.
—Jessica Hamzelou
This story is from The Checkup, our weekly biotech publication. Sign up to obtain it in your inbox each Thursday.
The must-reads
I’ve combed the web to seek out you right now’s most enjoyable/essential/scary/fascinating tales about expertise.
1 Anthropic says its fashions hacked exterior organisations throughout testing
It was prompted to conduct a assessment after comparable points at OpenAI. (TechCrunch)
+ Inside OpenAI’s hack of Hugging Face. (New Yorker $)
+ OpenAI referred to as the Hugging Face assault unprecedented. But we’ve been right here earlier than. (MIT Technology Review)
2 Europe is bracing itself for an much more fiery future
Countries like France and Spain can anticipate regimes akin to these in California. (Nature $)
+ Even the UK is experiencing fires now, too. (Guardian)
+ El Niño is partly accountable for this yr’s grueling heatwaves. (Wired $)
+ District cooling might assist beat excessive warmth in cities. (New Scientist $)
3 Drone warfare is making the skies extra harmful
A deadly airplane accident within the US this May, attributable to a navy GPS jamming train, might sign what’s to come back. (Wired$)
+ Zelensky requested Trump to safe Musk’s permission for the usage of Starlink to information drone strikes inside Russia this week. (The Atlantic $)
4 As Big Tech’s AI spending grows, so do the jitters
Amazon, Google, Meta and Microsoft are set to take a position $1.5 trillion into AI infrastructure. But who pays for it? (NYT $)
+ Are buyers actually getting chilly toes concerning the AI growth? (FT $)
+ An AI-focused hedge fund simply imploded. (CNBC)
5 How China has modified the sovereign AI playbook
Kimi 3 from Moonshot makes forking out for costly US fashions appear silly. (Rest of World)
+ The US is successful on the innovative. But China dominates low-cost fashions. (CNBC)
+ Could AI find yourself too low-cost to regulate? (Vox $)
6 Google’s Gemini can now management a humanoid robotic
It was beforehand restricted to higher physique actions. Now, it could actually handle all the vary of movement. (Bloomberg $)
+ These gig employees are coaching humanoid robots at house. (MIT Technology Review)
7 Amazon says it’s discovered “catastrophically costly” AI value overruns
It’s removed from alone—and that’s why the “tokenmaxxing” pattern disappeared so shortly. (FT $)
8 How a distant indigenous group constructed a brilliant quick fiber community
It was a fancy, costly endeavor. But it now outperforms Starlink. (IEEE Spectrum)
+ Stratospheric web might lastly begin taking off this yr. (MIT Technology Review)
9 Meet Wikipedia’s most diligent editor
Steven Pruitt is unremarkable in some methods—but really superb in others. (New Yorker $)
10 You can now report AI slop with a button on LinkedIn
The folks have spoken. And they’re uninterested in studying bland nonsense. (404 Media)
Quote of the day
“It’s a shock, pondering that simply an hour earlier I’d been in my room and every little thing… and now, there’s nothing left.”
—18-year-old Raphael Fohanno tells Reuters his response to wildfires destroying his mother and father’ home within the French city of Biscarrosse.
One More Thing

Congress used to guage rising applied sciences. Let’s do it once more.
The US Office of Technology Assessment, an unbiased workplace created by Congress within the early Nineteen Seventies, produced some 750 stories throughout its 23-year historical past, assessing applied sciences as assorted as digital surveillance, genetic engineering, and distant sensing from outer area.
The workplace functioned like a debunking arm. It sussed out the snake oil. Its stories noticed via the alluring gleam of overhyped applied sciences.
Since its unceremonious defunding in 1995, perennial calls have gone out: Rouse the workplace from the lifeless!
Read our story about why, with advances in robotics, massive information, and AI methods, these calls have taken on a brand new degree of urgency.
—Peter Andrey Smith
We can nonetheless have good issues
A spot for consolation, enjoyable, and distraction to brighten up your day. (Got any concepts? Drop me a line.)
+ Fencing on curler skates is the self-defense you didn’t know you wanted.
+ Meet Pumpkin, a chubby cat that’s in no temper to shed pounds.
+ Discover what the animals close to you’re most likely doing proper now at Nature This Week.
+ Woodworker extraordinaire Matt Thompson has put in a mannequin railroad that runs alongside his fence.



